[Audio] Role Play Trimethoprim /Sulfamethoxazole For UTI Monia Aljumah – 202010036 Maryam Hikal 202010972.
[Audio] Monia: Good morning Dr Maryam. I'm Monia a medical rep from G-S-K company here to discuss a reliable option for treating urinary tract infections—trimethoprim/sulfamethoxazole. Dr Maryam: Good morning Monia. utis are a prevalent concern in urology so I'm interested to hear about this treatment. Please have a seat..
[Audio] Monia: Thank you. Trimethoprim/sulfamethoxazole also known as Bactrim or Septra has shown efficacy against common uropathogens like Escherichia coli making it a valuable option for uncomplicated utis. Dr Maryam: That's encouraging to hear. What dose of trimethoprim/sulfamethoxazole is typically recommended for U-T-I treatment and how does it correlate with the clinical evidence?.
[Audio] Monia: The standard dose for uncomplicated utis in adults is typically 160/800 milligrams (trimethoprim/sulfamethoxazole) twice daily for 3 days. This dosing regimen has been supported by clinical studies demonstrating high cure rates and symptom resolution in U-T-I patients. Dr Maryam: That's helpful information. Could you elaborate on the clinical evidence supporting the use of trimethoprim/sulfamethoxazole for utis?.
[Audio] Monia: Certainly. Several randomized controlled trials have compared trimethoprim/sulfamethoxazole to other antibiotics commonly used for utis such as nitrofurantoin and fluoroquinolones. These studies have consistently shown comparable effectiveness in achieving bacterial eradication and symptom relief reinforcing its role as a first-line treatment option for uncomplicated utis and it’s F-D-A approved. Dr Maryam: I appreciate hearing about the clinical data supporting its efficacy. What about safety considerations especially regarding potential adverse effects?.
[Audio] Maryam: Trimethoprim/sulfamethoxazole is generally well-tolerated but like any antibiotic it can cause side effects such as nausea vomiting and allergic reactions. Renal function should also be monitored particularly in patients with preexisting kidney issues. Dr Monia: Understood. I always emphasize the importance of monitoring and patient education regarding potential side effects. Regarding antibiotic resistance do you have any insights into the evolving resistance patterns related to trimethoprim/sulfamethoxazole?.
[Audio] Maryam: Resistance to trimethoprim/sulfamethoxazole has been observed especially in regions with high rates of ESBL-producing bacteria. However prudent use and consideration of local resistance data can help minimize resistance development and preserve the efficacy of this antibiotic. Dr Monia: That's a crucial consideration in our approach to antibiotic prescribing. Overall trimethoprim/sulfamethoxazole seems to be a valuable option for uncomplicated utis especially with supported by numerous clinical studies and meta-analyses..
[Audio] Maryam: Absolutely Dr Patel. If you need any further information or support regarding trimethoprim/sulfamethoxazole or other antibiotics please feel free to reach out. I'm here to assist you and your patients. Dr Monia: Thank you Maryam. Your insights have been valuable and I appreciate your dedication to promoting responsible antibiotic use and patient care..
[Audio] Maryam: It's my pleasure Dr Monia. Have a great day and I look forward to our continued collaboration in managing utis effectively. Dr Monia: Likewise. Take care Maryam..