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H. G.
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ANTIANGINAL DRUGS.
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Angina pectoris?. Angina pectoris. Major symptom of Ischemic heart disease..
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Angina pectoris has 3 patterns. stable angina. Unstable angina.
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Stable angina. Most common form. Angina pectoris has 3 patterns.
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Antianginal drugs. Treatment strategies. Types. Mechanism of action.
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Treatment strategies. Dilate coronary blood vessel.
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TYPES OF ANTIANGINAL DRUGS. Antianginal drugs β - blockers Calcium channel blockers Nitrates.
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Beta Blocker. Free vector cartoon style heart illustration.
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Mechanism of action. By blocking beta receptor ↓ oxygen demand ↓ Heart rate, contractility ↓ Cardiac output and blood pressure.
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Most common side effects of beta blockers are:. Bradycardia.
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Inhibit calcium channel in arterial smooth muscle causing relaxation and vasodilation.
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Side Effects of calcium channel blockers. Flushing.
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Organic Nitrates. Administered nitrates ↑ nitrate Nitric oxide cGMP DEPHOSPHORYLATION OF MYOSIN LIGHT CHAIN VASCULAR SMOOTH MUSCLE RELATION.
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Types of Nitrates. Short acting nitrates Glyceryl trinitrate.
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Long acting nitrates • Isosorbide dinitrate. Types of Nitrates.
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Side Effects of Nitrates. Headache. Postural hypotension.