Shipping Non-Hazardous Biological Materials with Dry Ice

[Audio] Shipping Non-Hazardous Biological Materials with Dry Ice.

[Audio] Preparation of shipments of non-hazardous and/or unregulated materials/ biologicals/medical devices with DRY ICE under Department of Transportation ( DOT) and International Air Transport Association ( IATA) regulations. Non-hazardous/Non-Regulated materials shipped with DRY ICE at Organogenesis include – DERMAGRAFT™, trypsin, BPE, media samples (sent for further testing), cells and other samples which are NOT expected to contain pathogens. Dry ice is a hazardous material and as such it is regulated for shipment by the United States Department of Transportation ( USDOT) and the International Air Transport Association (IATA). Regulations require that specific procedures must be followed when shipping dry ice. This training only covers procedures to follow when your shipment includes no chemically or biologically hazardous materials other than dry ice. Pay particular attention to any preservatives or buffers that your sample may be in, eg., ethanol, formalin, formaldehyde, etc., DO NOT SHIP! Contact EHS (x1208). If you are not sure if the material you are shipping is considered hazardous, contact EHS..

[Audio] The materials listed below are NOT subject to DOT or International Air Transport Association ( IATA) shipping regulations, however, international shipments of these materials may still require additional permitting and or/ customs forms completion. Contact shipping with questions regarding international shipments.

OSHA Bloodborne Pathogen Standard Requirement. Biohazard Label on Interior storage container (NOT an outer shipping box) Non-Infectious biologicals from human, animals, or plants. Non-infectious cells, tissue cultures, blood or plasma from individuals not suspected of having an infectious disease, DNA, RNA, other genetic elements Dried Blood spots Fecal occult blood screening tests Tissues or organs for use in transplantation.

[Audio] For example the "exempt human specimens" label would be required on shipping boxes used by tissue donation facilities..

[Audio] Hazardous materials are essential for the economy of the United States and the wellbeing of its citizens. Millions of tons of hazardous materials are transported every day. They are moved by plane, train, truck, and vessel. The quantities in these shipments range from a few ounces to many thousands of gallons. In the wrong hands hazardous materials can pose a significant threat. Some of them are easily transformed into terrorist weapons. Addressing this threat is vital to protecting our citizens and our economy. What if a cargo of chlorine gas is hijacked and released at a large public event such as a professional football game? This unthinkable act is possible, thus the security of hazardous materials in transportation is of critical importance. While many of the materials classified by the DOT as hazardous materials are essential products for industry, they also represent potential deadly weapons in the hands of a terrorist. Some relatively simple chemical mixtures can cause a powerful explosion if detonated or ignited. The task of securing hazardous materials against unauthorized access is daunting. For example, the transportation of gasoline and propane requires a nation-wide fleet of 85,000 trucks. Law enforcement agencies alone cannot guarantee the safety of these trucks or the security of our transportation system. The help of everyone involved in the transportation of hazardous materials, including shippers both large and small, is needed to secure the transportation system. What can you do to prevent or deter unauthorized access to potentially lethal hazardous materials? Start with an evaluation of your specific operation to identify its vulnerabilities. Concerning hazardous materials security, you should consider keeping storage areas locked, restricting access by non-employees, and keeping updated and accurate inventories..

[Audio] Before we can address specific shipping and transportation requirements, a better understanding of how hazardous materials are defined and categorized is required. A. Definition of Hazardous Material A hazardous material is generally defined as any substance that could adversely affect the safety of the public, handlers or carriers during transportation. Hazardous material, as defined by the DOT, is any substance that appears in the 49 CFR Hazardous Materials Table.

[Audio] YOU ARE NOT TRAINED TO SHIP ANYTHING IN CLASSES 1- 8!!! If the items that you intend to ship contains a chemical that could fall under a category other than 9 DO NOT SHIP.

[Audio] 1. Explosion hazard: dry ice releases large volumes of carbon dioxide gas as it sublimates. If packaged in a container that does not allow for release of this gas, it can explode, causing personal injury and/or property damage. 2. Suffocation hazard: a large volume of carbon dioxide gas emitted in a confined space can create an oxygen deficient atmosphere. 3. Contact hazard: dry ice is a cryogenic material that causes severe frostbite upon contact with skin. Following the procedures outlined in this guide will minimize risk for all during transportation. With a package designed to vent gaseous carbon dioxide, the explosion hazard will be eliminated, and by labeling the package properly, the suffocation and contact hazards will be greatly reduced..

Packaging Requirements Per IATA. Venting Gas Must allow for the release of carbon dioxide gas NEVER be put in a container with an airtight seal Package Integrity Adequate strength for its intended use Strong enough to withstand the handling normally encountered in transport Constructed and closed in order to prevent any loss of contents that might be cause by vibration or by changes in temp, humidity, or altitude Package Materials Do NOT use plastics that can be rendered brittle or permeable by the temp. of dry ice Use commercially available packages intended to contain dry ice Approved boxes are available through our warehouse.

Preparing Shipment. Ensure that packages are free from damage and conform to Packing Instructions 954 Ensure that the quantity of dry ice does not exceed 200 kg per package Wear gloves and other PPE.

Marking and Labeling: Outermost (Shipping Box). Hazard class 9 Label Proper Shipping Name: UN 1845, Dry Ice (or Carbon dioxide, solid) The net weight of dry ice in kilograms must be written on package label. Labels available through EHS or shipping department Label is affixed to a vertical side of the box and oriented as shown. Full name, address, telephone number of shipper and consignee need only be listed if it is not on the airway bill.

[Audio] The shipper does NOT need to complete the areas for " Shipper" and " Consignee" as long as a proper completed airway bill accompanies the package..

Documentation: Airbill. If you are using the FedEx Computer software to complete the airbill Complete required information including package and shipment details. Once you have selected a “package type”, if you press the “OPTIONS” tab you will open a screen where you will see “Special Service” Check off – DRY ICE and you will be able to enter the weight of the dry ice. Note: Until you have the package information, the option tab will not contain this information.

O: XXXA M Fom: 123 Front st- TO. 075 47077621 Mary Smith 5234 Wtndtester Another City Postal Code SHPtÄT: nxxxm KGS ACT.JALWGI t2 SFtun• FOR TRAINING PURPOSES ONLY Check your Airbill. It must have the following information or it will not be accepted by FedEx!! I) 2) 3) Shippers Address Recipient Address Net Quantity of Dry Ice II II II Ill II Ill II II I II II : Ill Ill II II II III I Ill TRK# 2986 1588 9018 Emp AM INTL PRIORITY ICE 888888 xx-xx.

[Audio] If an accident were to occur with your package it is important that the material inside can be easily identified, even if it is nonhazardous. Description to be included..

[Audio] Do not write " specimen", "diagnostic specimen", "biological specimen" or any other words, other than what is required as outlined in this document Do NOT affix a " biohazard" label, to the outermost container. Specimens fall under specific regulatory guidelines and requirements. Confusion regarding the contents of your package may lead to delivery delay and more importantly, fines from regulatory organizations. If a shipment needs biohazard symbol warnings in accordance with the OSHA Bloodborne Pathogen Standard, affix stickers to the INSIDE container. • Secure your samples in such a way that when the dry ice sublimates, they will not move freely inside of the insulated box. This can be accomplished by wedging your samples in place with cardboard or Styrofoam. Fragile containers such as glass tubes or vials should be wrapped with cushioning material. • Minimize the volume of air to which the dry ice is exposed in order to slow the rate of sublimation. If there is any air space after you fill your package with dry ice, fill it with packing peanuts or other material to reduce the volume of air space. • Shipments are generally recommended to contain 5- 10 pounds ( 2.27- 4.54 kg) of dry ice per 24 hours. Refer to your package manufacturer's recommendations. Make arrangements with your consignee to make sure your package will be received on its intended delivery date. Take into account local holidays or closings that might delay package receipt. • Dry ice shipments can be made with FedEx and DHL. UPS and the U.S. Postal Service have extremely restrictive policies concerning shipments of hazardous materials; EHS recommends that you do not ship dry ice with UPS or the U.S. Postal Service. • ALL.

[Audio] • If you are shipping a liquid, pack it in such a way THAT IT WILL NOT LEAK during transport!! Even nonhazardous liquids can create regulatory issues if they break open on a flight. Always use positive closures and secondary containment for liquids ( zip-locks). Absorbent materials should be placed between your primary and secondary containers to contain leaks. Absorbents are available through Fisher Scientific. • Reusing a dry ice shipping box is a good use of resources. If you choose to reuse a box, completely cover or obliterate all unnecessary marking such as hazard labels, addresses, old FedEx (or other courier) labels and/or barcodes. Only reuse a box if you can personally verify it is not contaminated and its integrity is intact. A box should not be reused if it is torn, cut, stained, or if the insulation is cracked or broken..

[Audio] Secure your samples in such a way that when the dry ice sublimates, they will not move freely inside of the insulated box. This can be accomplished by wedging your samples in place with cardboard or Styrofoam. Fragile containers such as glass tubes or vials should be wrapped with cushioning material. • Minimize the volume of air to which the dry ice is exposed in order to slow the rate of sublimation. If there is any air space after you fill your package with dry ice, fill it with packing peanuts or other material to reduce the volume of air space. • Shipments are generally recommended to contain 5- 10 pounds ( 2.27- 4.54 kg) of dry ice per 24 hours. Refer to your package manufacturer's recommendations. Make arrangements with your consignee to make sure your package will be received on its intended delivery date. Take into account local holidays or closings that might delay package receipt. • Dry ice shipments can be made with FedEx and DHL. UPS and the U.S. Postal Service have extremely restrictive policies concerning shipments of hazardous materials; EHS recommends that you do not ship dry ice with UPS or the U.S. Postal Service. • ALL.

Intent to Ship Drv Ice Aftex leading this Guide to Shipping Ice, complete the following EHS review the completed form and, upon successful completion, certi$• you to ship dry ice. The certification expire after two years result in fines and l) What are the 3 reasons that dry ice considered a hazardous material? 2) Of the appeal package Check Net weigh* gfdO ia 'Biolo&tal "tr•üS45, Dry ice" Clan 9 b.rd label z Biobayrd Class S b.rd label z wi±presaibed 3) A class 9 label most be put on a package only When there axe other haut-dons materials in the box in to a) Tme b) False 4) It acceptable to put a class 9 label on top o: bottom of the box a) Tme b) False 5) Make to completely seal the Sti10f01m packing tape leak Of catboa dioxide during transport. b) False 6) The only consideration when reusing a dry ice shipping box is labeling it "'ith the correct address. b) False I nnderstlnd the hazards rssociated vith dry ice and dale Shipping reqQements dg iæ, 15 ontlined this manna-I. Print Name: Sig-natn,se: LIST MATERIAL(S THAT YOU ARE SHIPPING WITH DRY ICE Department Date: * *Submit to.

Shipping Dry Ice. According to the OSHA Bloodborne Pathogens Standard, where should a Biohazard Label be displayed when shipping Dry Ice?.

PPE. When shipping dry ice there is no need for any sort of PPE..

Labeling. It is important to write things on the shipment such as "specimen", "diagnostic specimen", "biological specimen" to discribe what is being shipped..

Unregulated Biological Materials. Which one of the following is not classified as a biological material?.

Results. Below you will find the results of the scored questions in this course. When you are finished, click Exit to close the course..