Vaccine History

Vaccine History. Dr. Cameron. Primary Source: https://www.historyofvaccines.org/timeline/all.

First Uses of “Vaccines”. Diagram Description automatically generated with low confidence.

1648 Quarantine in Boston. In response to epidemics of yellow fever in Barbados, Cuba, and the Yucatan, a strict quarantine was established in Boston, Massachusetts, for all ships arriving from the West Indies because of “ye plague or like infectious disease..

1721 – Variolation in England – Lady Mary. The results, were sometimes fatal: two to three percent of those variolated died of smallpox (in contrast to 20-30% who died after contracting smallpox naturally). What’s more, variolated individuals could pass the disease on to others..

1721 – United States - Onesimus. An African slave sold to Cotton Mather shared his experience with inoculation of smallpox. This knowledge is credited with saving thousands of lives in the American colonies..

The response….. According to Mather, they “raised an horrid Clamour .” Their rage came from many sources; fear that inoculation might spread smallpox further; knowledge that the bubonic plague was on the rise in France; and a righteous fury that it was immoral to tamper with God’s judgment in this way. There was a racial tone to their response as well, as they rebelled against an idea that was not only foreign, but African. Some of Mather’s opponents compared inoculation to what we would now call terrorism —as if “a man should willfully throw a Bomb into a Town.” Indeed, one local terrorist did exactly that, throwing a bomb through Mather’s window, with a note that read, “COTTON MATHER, You Dog, Dam You; I’l inoculate you with this, with a Pox to you.”.

Smallpox. Smallpox is the only disease that we have ever successfully eradicated, and it was done entirely through vaccination..

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1774 – Benjamin Jesty. English farmer and cattle breeder, inoculated his wife and two sons with matter from a cowpox lesion on one of his cows. Jesty, having already contracted cowpox, believed himself protected from smallpox infection. When a serious smallpox epidemic hit his Dorset village, he, from his “great strength of mind,” took it upon himself to protect his family. His wife and children survived, and the boys, when challenged with smallpox inoculation in 1789, showed no symptoms. Jesty, however, had no interest in systematically testing his methods or publishing his results, and so his finding was largely forgotten..

abstract. 1777- George Washington issues first vaccine mandate.

1796 – Edward Jenner. Using pus from the milkmaid, Sarah Nelms, Edward Jenner vaccinated 8-year-old, James Phillips. Scientific evidence of vaccination was born..

1805 - France. . Marianne Elisa of Lucca (Napoleon’s sister) became the first ruler to try making vaccination compulsory..

VACCINATION TO ORDER. The Probable Situation if •the Board Of Health Attempts to Enforce Its , Recent Command. en ner.

1861 - Measles. Text Description automatically generated.

1861 – Louis Pasteur, Germ Theory. Understanding that microscopic organisms are responsible for sickness..

Ill I I I mn mn 11tn "iii. 1874 - Germany. A compulsory smallpox vaccination and revaccination law went into in effect in Germany. Over the next decades, smallpox deaths there dropped rapidly..

1879 –Louis Pasteur. . Louis Pasteur produced the first laboratory-developed vaccine: the vaccine for chicken cholera ( Pasteurella multocida ). Pasteur attenuated, or weakened, the bacteria for use in the vaccine. He happened upon the method of attenuation by accident.

1882 – Antivaccination League. The Anti-Vaccination League of America held its first meeting in New York. Among the assertions made by the speakers at the meeting was the idea that smallpox was spread not by contagion, but by filth . This became a popular, though incorrect, argument of anti-vaccinationists..

1893 – Muncie, Indiana. This girl survived a serious case of smallpox during the 1893 Muncie, Indiana, smallpox epidemic.

1899 – Panama Canal. The French officially abandoned efforts to build the Panama Canal and transferred the rights to the project to the United States, in part because of the yellow fever and malaria deaths among the project’s workers..

(Jacobson v. Massachusetts).. In 1 905 the Supreme Court ruled in support of mandatory vaccinations..

1905 -Forced Vaccinations. S hortly after the 1905 ruling by the Supreme Court, in some cities, Public Health officials and Law enforcement went door to door physically forcing vaccines on the unvaccinated..

1906 – Opposition Grows. In 1926, a group of health officers visited Georgetown, Delaware, to vaccinate the townspeople. A retired Army lieutenant and a city councilman led an armed mob to force them out , successfully preventing the vaccination attempt..

Spanish Flu of 1918. When influenza hit in 1918 shutdowns ensued and people were made to mask - even in their own homes! Churches were canceled, schools were closed, extreme measures were taken to preserve lives. The Anti-mask League was born..

1948 Kyoto, Japan. Ca 1948 PPC Ori Dono Textile Gallery Kyoto Japan Mint eBay.

1949 - Hidalgo Country, Texas.. The last 8 cases of polio in the United States..

1951 - Greenland. Measles arrived in Greenland with a final attack rate of 99.9%.

1955 – The Cutter Incident. It soon emerged that most of the cases of paralytic polio occurred in children inoculated with vaccine produced by Cutter Laboratories in California..

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1964 –Rubella Outbreak. Pediatric Rubella in Emergency Medicine Background Pathophysiology Epidemiology.

1977 – Childhood Immunization Initiative.. In 1977 the US government introduced the Childhood Immunization Initiative and people began to protest - they didn't believe the vaccines were necessary and many expressed concerns that the government was violating their rights. Misinformation began to take hold and the anti-vaccine movement was officially born..

1980 – Smallpox officially eradicated. World Health Organization scroll of Declaration of Smallpox Eradication.

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