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Signaling Pathway NF-KB (Nuclear Factor Kappa light chain enhancer of activated B-cells).
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NF-KB Signaling Pathway. Family of highly conserved transcription factors..
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Complications. NF-KB signaling pathway is involved in diseases such as,.
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Components of the Pathway.
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In mammals, composed of five related transcription factors..
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Signaling Pathways.
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NFKB has two distinct signaling pathways known as:.
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Canonical Pathway.
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The canonical NF-κB is activated by various stimuli, transducing a quick but transient transcriptional activity, to regulate the expression of various proinflammatory genes and also serve as the critical mediator for inflammatory response..
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The canonical NF- κB is activated by various stimuli, transducing a quick but transient transcriptional activity, to regulate the expression of various proinflammatory genes and also serve as the critical mediator for inflammatory response..
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Non Canonical Pathway.
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Involved in processes like:. B cell Maturation. Osteoclast Differentiation.
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Involved in processes like: B cell Maturation Osteoclast Differentiation Lymphoid Organogenesis.
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Thanks!. Group 6 Anoosha Ahmed Taimoor Musharaf M. Asim Siddiqui Nimra Abaid Zainab Irfan.
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Template was taken from www.slidesgo.com Pathway images were obtained from www.biorender.com Images and vectors were obtained from Freepik..