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CARBAMAZEPINE 100 MG 200 MG 400 MG CHEWABLE TABLET IMMEDIATE RELEASE TABLET EXTENDED RELEASE TABLET

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WHAT RESULTS MAY BE EXPECTED FROM TAKING IT?

Carbamazepine is used alone or in combination with other medications to control certain types of seizures in people with epilepsy.  used to treat trigeminal neuralgia Carbamazepine extended-release capsules are also used to treat episodes of mania or mixed episodes in patients with bipolar I disorder.

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For epilepsy, carbamazepine works by stopping electrical signals from building up in the nerve cells in the brain. It also reduces the release of a chemical (neurotransmitter) called glutamate. Too much glutamate can cause seizures. For nerve pain, carbamazepine works by stabilising the electric signals in your nerves. This stops the pain signals being sent to your brain.

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If you take carbamazepine twice a day, try to space your doses evenly through the day. For example, first thing in the morning, and in the evening. You can take it with or without food

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ARE THERE ANY SPECIAL INSTRUCTIONS ON HOW TO USE THIS MEDICATION?

For people with liver disease: This drug is not recommended for use with severe liver disease as it may make the condition worse. For people with heart disease: If you have any damage to your heart or an abnormal heart rhythm, this drug may make it worse. For pregnant women: This drug is a category D pregnancy drug.

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For women who are breastfeeding: This drug passes into breast milk. Carbamazepine should be taken with meals to lessen unwanted effects.

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DOES FOOD HAVE ANY EFFECT ON THIS MEDICATION?

Drinking grapefruit juice while taking this drug can cause higher levels of the drug in your body. This raises your risk of side effects.

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DO ALCOHOLIC BEVERAGES HAVE AN EFFECT ON THIS MEDICATION?

Avoid alcohol. Ingesting alcohol may increase drowsiness and dizziness.

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HOW LONG SHOULD I CONTINUE TAKING THIS MEDICATION?

If you have epilepsy or bipolar disorder, it's likely that once your condition is under control you will still need to take carbamazepine for several years. If you have nerve pain, once the pain has gone you will need to take carbamazepine for several months to stop it coming back.

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If you forget to take your dose, take it as soon as you remember. If it’s just a few hours until the time for your next dose, only take one dose at your scheduled time. Never try to catch up by taking two doses at once. This could cause dangerous side effects.

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WHICH SIDE EFFECTS SHOULD I REPORT, AND WHICH ONES MAY I DISREGARD?

The more common side effects that can occur with carbamazepine include: nausea vomiting problems with walking and coordination dizziness Drowsiness

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Serious side effects and their symptoms can include the following: severe skin reaction low blood cell counts heart problems liver problems suicidal thoughts low sodium levels in your blood

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This drug must be stored at the right temperature. Immediate-release tablets: Don’t store this drug above 86°F (30°C). Keep this drug away from light. Keep it away from high temperature. Don’t store this medication in moist or damp areas, such as bathrooms. Extended-release tablets: Store these tablets at 77°F (25°C). You can store them briefly at a temperature between 59°F and 86°F (15°C and 30°C). Keep this drug away from light. Keep it away from high temperature. Don’t store this medication in moist or damp areas, such as bathrooms.

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HOW LONG SHOULD I WAIT BEFORE REPORTING IF THIS MEDICATION DOES NOT HELP ME?

It can take 1 to 2 weeks for carbamazepine to work properly.

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DO I HAVE TO TAKE SPECIAL PRECAUTIONS WITH THIS MEDICATION IN COOMBINATION WITH ANY PRESCRIPTION MEDICATIONS, OTC, OR HERBAL PRODUCTS?

Exercise caution with St. John's Wort. This herb induces the CYP3A metabolism of carbamazepine and may reduce its serum concentration.

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Heart drugs diltiazem verapamil Fungal infection drugs ketoconazole itraconazole fluconazole voriconazole

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Anti-allergy drug Antibiotics clarithromycin erythromycin ciprofloxacin HIV drugs ritonavir indinavir nelfinavir saquinavir

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Mental health drugs fluoxetine fluvoxamine trazodone olanzapine loxapine quetiapine Anti-spasm drug dantrolene Bladder drug oxybutynin  carbamazepine

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Blood thinners rivaroxaban apixaban dabigatran edoxaban Heartburn drugs cimetidine Omeprazole Anti-seizure drugs felbamate methsuximide phenytoin fosphenytoin phenobarbital primidone

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Anti-seizure drugs phenytoin phenobarbital valproic acid Herbal products Niacinamide Pain drug Ibuprofen Anti-rejection drug tacrolimus

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Cancer drugs cisplatin doxorubicin temsirolimus lapatinib cyclophosphamide

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Bipolar disorder drug lithium  Hormonal birth control drugs Respiratory drugs aminophylline Theophylline Muscle relaxers pancuronium vecuronium rocuronium cisatracurium

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IS MY PRESCRIPTION RENEWABLE AND FOR HOW LONG OF A PERIOD MAY IT BE RENEWED?

A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

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DOES THIS MEDICATION COME IN A LESS EXPENSIVE GENERIC FORM?

Carbamazepine oral tablet is available as the brand-name drugs Tegretol, Tegretol XR, and Epitol. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.

CARBAMAZEPINE

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